Chitosan Nanoparticle And Its Application In Non- Parenteral Drug Delivery

نویسندگان

چکیده

This study's main goals are to give an overview of chitosan-based nanoparticles used in a variety non-parenteral applications and call attention new research on mucoadhesive sustained release chitosan dosage forms. Chitosan is biodegradable, biocompatible polymer that has been certified for use wound dressings suitable inclusion human diets. For drug delivery methods, employed as carrier polymeric nanoparticles. with numerous possible uses since it chemical functional groups can be altered serve particular purposes. The positive surface charges qualities (np) made derivatives enable them stick mucous membranes gradually the therapeutic payload. review will include examples techniques treating eye infections, cancer, gastrointestinal disorders, pulmonary cancer. Both vitro few vivo investigations show low level toxicity. looks at recent characteristics, modifications, toxicity, pharmacokinetics, preclinical trials delivery.

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ژورنال

عنوان ژورنال: Journal of Pharmaceutical Negative Results

سال: 2022

ISSN: ['0976-9234', '2229-7723']

DOI: https://doi.org/10.47750/pnr.2022.13.s03.292